Acrodermatitis enteropathica in a full-term breast-fed infant.

Symptomatic zinc deficiency in a breast-fed preterm infant.

A 2-month-old preterm boy who developed symptomatic zinc deficiency while being exclusively breast fed is described. Oral zinc supplements induced a complete remission but mucosal 65Zn uptake studies and metabolic balances conducted before and after withdrawal of the supplements excluded the diagnosis of acrodermatitis enteropathica. By age 12 months the boy was well and no longer required zinc...

[Acrodermatitis enteropathica in a breast-fed infant].

Acrodermatitis enteropathica in a full-term breast-fed infant: case report and literature review.

, 1056–1057 © 2008 The International Society of Dermatology 1056 A male full-term infant, who had been exclusively breast-fed since birth, at 2 months of age developed an erythematous, scaling eruption involving the face (in a periorificial distribution, i.e. mouth, nose, ears, and eyes), hands, and feet, which did not respond to treatment with topical corticosteroids and oral antimicrobials. H...

A Methylmalonic Acidemia Case Presenting with Acrodermatitis Enteropathica

We encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. This child was being fed with a low-protein diet when the skin disorder developed. A deficiency in plasma levels isoleucine, was confirmed. Supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. We assume that in our patient the sk...

Blueprint Genetics

Acrodermatitis enteropathica (AE) is caused by SLC39A4 mutations leading to severe zinc deficiency and manifest clinically by acral dermatitis, alopecia, diarrhea and growth failure. AE usually presents in the first months of life in infants that are not breast-fed and at the time of weaning in breast-fed infants, as cow’s milk contains more zinc-binding phytates that impede zinc absorption. In...